Disease: Adult Myelodysplastic Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
WRN Q14191 WRN RecQ like helicase Enzyme 2.6E-34 0.524 0.808
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
TPMT P51580 thiopurine S-methyltransferase 7.1E-06 0.593 0.692
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
THPO P40225 thrombopoietin 0.20 0.513 0.692
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
TERC telomerase RNA component 0.471 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SLC17A5 Q9NRA2 solute carrier family 17 member 5 Transporter 6.9E-10 0.491 0.808
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SCT P09683 secretin 1.4E-07 0.484 0.846
SBDS Q9Y3A5 SBDS ribosome maturation factor Enzyme 6.2E-05 0.601 0.692
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
RPS19 P39019 ribosomal protein S19 Nucleic acid binding 0.92 0.480 0.846
RPS14 P62263 ribosomal protein S14 Nucleic acid binding 0.90 0.631 0.500
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
RARA P10276 retinoic acid receptor alpha Nuclear receptor 0.96 0.470 0.846
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808